Blog | HemaCare

HemaCare PBMCs Aid HPV Cancer Research

Apr 7, 2020 10:07:00 AM / by Nancy Andon, MSc posted in Cancer, PBMCs, T Cells

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Cell therapy starting materials sourced from HemaCare are being used to support studies focused on the selective expansion of tumor-specific T cells.

In a recent article, [1] researchers at a Cambridge, MA biotech company describe their work with a fusion protein designed to specifically activate and expand killer T cells that recognize human papilloma virus associated (HPV+) head and neck cancer cells.

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X-ALD Patients Hope to See Results With Cell-Based Gene Therapy

Mar 31, 2020 10:06:00 AM / by Stacy Matthews Branch, DVM, PhD posted in Gene Therapy, Bone Marrow, Cell Therapy, CNS/Neurodegeneration

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As Phase 3 clinical trials begin for Lenti-D as a treatment for patients with X-ALD, the drug also shows promise for treating a range of neurodegenerative diseases.

X‐linked adrenoleukodystrophy (X‐ALD) is a peroxisomal disorder resulting from a mutation in the human ATP-binding cassette, sub-family D, member 1 gene (ABCD1). The ABCD1 gene codes for the adrenoleukodystrophy protein (ALDP) needed for very-long-chain fatty acids (VLCFAs) to enter peroxisomes for degradation. When this process is disrupted, the VLCFAs accumulate in various tissues of the body, including the brain. VLCFA accumulation and demyelination of brain white matter lead to the severe neurological symptoms seen with X-ALD.

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Discussing Therapeutic Options for Novel Coronavirus (COVID-19)

Mar 24, 2020 10:04:00 AM / by Stacy Matthews Branch, DVM, PhD posted in T Cells, Vaccine Research, Immunotherapy (Immunology)

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While the world waits for a coronavirus vaccine, scientists are looking to viral and cell therapy treatments for a solution.

Since China began reporting COVID-19 cases to the World Health Organization (WHO), the novel virus has since spread globally. With the declaration of COVID-19 as a global pandemic, announcements about efforts to develop a coronavirus vaccine are ongoing and constant.

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Memory T Cells in Mice Aid Immunity During Periods of Food Scarcity

Mar 17, 2020 10:12:00 AM / by Stacy Matthews Branch, DVM, PhD posted in T Cells, Immunotherapy (Immunology)

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Researchers are studying the importance of white adipose tissue and its role in storing memory T cells.

The idea that if you don’t eat enough, you’ll get sick may be true in some ways, but there is new information available revealing that the immune system may have a strategy to keep fighting infectious agents even when food is scarce.

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HemaCare Bone Marrow Mononuclear Cells Help Unravel Immunological Mystery

Mar 10, 2020 10:05:00 AM / by Nancy Andon, MSc posted in Bone Marrow, Immunotherapy (Immunology)

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Scientists in New York studying allergic disease have just published work citing the use of HemaCare-sourced bone marrow mononuclear cells for their research into the mechanisms of immunological memory.

The immune system is a wonderfully complex assembly of interacting cells and tissues that protect us from disease. To function properly, the cells within this system must detect and remember a wide variety of triggering agents.

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