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Nancy Andon, MSc


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HemaCare Starting Material Plays Key Role in Dendritic Cell Assay Development

Mar 2, 2021 10:04:00 AM / by Nancy Andon, MSc posted in Dendritic Cells, PBMCs

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Pharmaceutical giant Pfizer cite the use of HemaCare starting materials in the development of a new immune cell validation assay. [1]

The new assay is designed to measure dendritic cell activation as a predictor of immunogenicity, so that scientists can assess risk early in the development of new pharmaceuticals. Low immunogenicity points toward a better overall safety profile.

Dendritic cells (DC) are antigen-presenting cells, involved in the initiation and regulation of the immune response. Since DC are tumor-infiltrating cells central to the initiation of antigen-specific immunity, they have long been investigated as a means of improving cancer immunotherapy.

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Cryopreserved T Cells Hold Answers to COVID-19 Immunity

Feb 16, 2021 10:05:00 AM / by Nancy Andon, MSc posted in PBMCs, T Cells

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In a recent publication, researchers at Cellular Technology Ltd. in the U.S., and Complutense University in Madrid, Spain cites using cryopreserved PBMCs from HemaCare for their COVID-19 research. [1]

The scientific group set out to answer one of the most important questions of the COVID-19 pandemic - how can we truly know whether someone has been exposed to the virus?

Widespread COVID-19 testing is helping governments and healthcare workers track the spread of the virus in an ongoing effort to isolate those who may be contagious from those who have not been exposed. However, most people exposed to SARS-CoV-2, the virus responsible for COVID-19, experience mild disease or are asymptomatic. This means that the presence of SARS-CoV-2-specific antibodies may fade quickly after infection, increasing the chance of a false-negative test result.

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HemaCare Macrophages Help Solve Mysteries of Immune Regulation

Jan 26, 2021 10:25:00 AM / by Nancy Andon, MSc posted in Cancer, Macrophages, Immunotherapy (Immunology)

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The use of HemaCare-sourced macrophages has been cited in a recent publication in the Journal of Immunology. The paper is a collaboration between the University of Maryland in College Park, and biopharmaceutical company AstraZeneca. [1]

The role of macrophages in the human immune system is not nearly as well-known as T cells or B cells, which are seemingly ubiquitous in the cell and gene therapy field. Like lymphocytes, macrophages are derived from hematopoietic stem cells. Unlike the lymphoid lineage, however, myeloid precursors ultimately produce in the macrophage an immune cell capable of both antigen presentation and phagocytic activity.

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Stronger Together: HemaCare and Cellero Join Forces

Jan 12, 2021 10:06:00 AM / by Nancy Andon, MSc posted in Cell Therapy

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HemaCare and Cellero are ringing in the New Year with the aspiration to be bigger and better!

Both cell supply companies are joining forces under the umbrella of Massachusetts-based Charles River Laboratories. The new coalition is a major part of Charles River’s strategy to expand its research and development capacity, by acquiring the expertise needed to bring cellular therapies all the way from sourcing starting materials through to commercialization.

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Happy New Year! The Top Ten HemaCare Blogs of 2020

Dec 16, 2020 10:04:00 AM / by Nancy Andon, MSc posted in T Cells, NK Cells, Vaccine Research

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Even as the New Year approaches, we are sure 2020 will never be forgotten!

The emergence of the COVID pandemic brought unprecedented challenges to all of us. At HemaCare we have been proud to see our cryopreserved leukopak products deliver timely aid to COVID-19 researchers by providing high-quality starting materials to a supply chain suddenly beset with disruptions. It comes as no surprise that several of the blogs in our “Top Ten” list are focused on COVID research carried out as scientists raced toward a vaccine.

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