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Nancy Andon, MSc


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Cryopreserved Leukopaks: Finding the Best Fit for Your Research Needs

Jul 7, 2020 10:03:00 AM / by Nancy Andon, MSc posted in Leukopak, GMP Cellular Therapeutics, Basic Research

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The product your lab chooses to fulfill their research needs largely depends on the stage of development. Are you conducting early drug discovery research involving several different candidates? Perhaps your company is involved in translational research, considering a lead candidate for clinical studies? What is your research budget? Choosing the right starting material for a specific project is a critical decision, but one that can sometimes be daunting.

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HemaCare Donor Recruitment Helps Solve Lung Cancer Puzzle

Jun 30, 2020 10:04:00 AM / by Nancy Andon, MSc posted in Cancer

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A recent independent study cited using whole blood collected from HemCare donors to carry out research into how lung cancer suppresses the immune system. [1]

Scientists at a Boston-based pharmaceutical company have been trying to puzzle out exactly how lung cancer cells are able to suppress the immune system, and prevent it from launching an effective response. While previous research has exposed cancer-associated fibroblasts (CAFs) as the primary culprits in this process, there is still little real knowledge of how these cells are able to interfere with immune cell function.

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Mimicking Memory Cell Activation

Jun 23, 2020 10:08:00 AM / by Nancy Andon, MSc posted in B Cells, PBMCs, T Cells

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An independent study carried out at a Cellular Technology Ltd. cites using HemaCare PBMCs in their efforts to replicate physiological B cell activation in an assay format. [1]

Memory B cells function as the foundation of the adaptive immune system, creating a physiological catalogue of foreign antigens that can be used to “recognize” invading pathogens and trigger an immune response. Memory B cells can survive for decades, creating long-term protection against diseases that have been encountered previously.

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HemaCare PBMCs Aid HPV Cancer Research

Apr 7, 2020 10:07:00 AM / by Nancy Andon, MSc posted in Cancer, PBMCs, T Cells

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Cell therapy starting materials sourced from HemaCare are being used to support studies focused on the selective expansion of tumor-specific T cells.

In a recent article, [1] researchers at a Cambridge, MA biotech company describe their work with a fusion protein designed to specifically activate and expand killer T cells that recognize human papilloma virus associated (HPV+) head and neck cancer cells.

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HemaCare Bone Marrow Mononuclear Cells Help Unravel Immunological Mystery

Mar 10, 2020 10:05:00 AM / by Nancy Andon, MSc posted in Bone Marrow, Immunotherapy (Immunology)

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Scientists in New York studying allergic disease have just published work citing the use of HemaCare-sourced bone marrow mononuclear cells for their research into the mechanisms of immunological memory.

The immune system is a wonderfully complex assembly of interacting cells and tissues that protect us from disease. To function properly, the cells within this system must detect and remember a wide variety of triggering agents.

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