Blog | HemaCare

STEM Outreach - HemaCare Style

Mar 12, 2019 10:12:00 AM / by Nancy Andon, MSc posted in science

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HemaCare is committed to supporting the next generation of science and technology professionals through community outreach and educational programs. In a world that is increasingly reliant on science and technology, STEM education provides students with the necessary skill sets to enter the modern workforce. The STEM (Science, Technology, Engineering, and Math) initiative is based on the premise that these fields should be taught using an integrative approach that focuses on real-world applications, rather than teaching each field in isolation. The hope is to instill in our young people not just the skills of their chosen field, but a more critical way of thinking, understanding, and exploring the world.

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Atopic Dermatitus More Severe for African Americans

Mar 5, 2019 10:10:00 AM / by Stacy Matthews Branch, DVM, PhD posted in Dendritic cells

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Research efforts across different disciplines are beginning to uncover biological factors that underlie racial differences in health status and disease severity. One common condition with a prevalence of 7.3 percent among U.S. adults is atopic dermatitis. In terms of prevalence and disease severity, African Americans are disproportionately affected when compared to European Americans.

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Combat Viral and Bacterial Infections with Targeted Immune Cells

Feb 26, 2019 10:02:00 AM / by Stacy Matthews Branch, DVM, PhD posted in Dendritic cells, immune system, immune cells

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Dendritic cell molecules within the body’s immune system can be modified to improve our ability to combat viral and bacterial infections. 

The body’s immune system is designed to protect it from invading organisms and other pathogens. However, the immune system alone may not always be able to combat viral and bacterial infections, and antimicrobial therapies are implemented. A different approach would be to manipulate or affect immune system cells to control infections. Researchers at the Scripps Research Institute, La Jolla, CA have discovered that immune system molecules exist that can make people more vulnerable to bacterial infections, and that modifying expression or function of these immune molecules can enhance resistance to detrimental bacterial infections.

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FDA Policy Changes will Accelerate Cell and Gene Therapy Approvals

Feb 21, 2019 10:02:00 AM / by Nancy Andon, MSc posted in FDA, gene therapy, GMP, cell therapy, gmp-compliant

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The U.S. Food and Drug Administration (FDA) has announced that they are adding staff and rolling out policy changes aimed at advancing the development of safe and effective cell and gene therapies. [1] The announcement came in the form of a press release on January 15th, citing that the new policies are a response to the current surge in cell and gene therapy products that the agency is handling. Based on the number of investigational new drug (IND) applications being submitted, the FDA projects a significant rise in the number of therapies that will be approved over the next few years:

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HemaCare Starting Material Aids Discovery of New Brain Tumor Treatment Strategy

Feb 19, 2019 10:02:00 AM / by Nancy Andon, MSc posted in T cells, Tumors

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An independent publication cites using HemaCare primary T-cells to investigate a novel cancer therapy based on blocking immune suppression while simultaneously promoting T-cell activity. [1]

Newly approved T-cell therapies have been eliciting enthusiastic discussion across the medical field for their unparalleled success rate in treating aggressive blood cancers. This success has unfortunately not extended to the treatment of brain tumors, where upregulation of the “immune checkpoint” molecule PDL-1 interferes with normal immune response. Now a research group based at the University of Alabama’s Medical School may have found a way to outsmart brain cancer cells that evade the body’s immune system.

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