Blog | HemaCare

Genetically Engineered T-Cells May Lead to a New Immunotherapy for Type 1 Diabetes

Aug 31, 2021 10:15:00 AM / by Stacy Matthews Branch, DVM, PhD posted in CAR-T, T Cells

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University of Arizona researchers created a new five-module chimeric antigen receptor T cell that has shown potential to fight against Type 1 diabetes.

Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of pancreatic β cells by pathogenic, autoreactive T cells. Effective and safe immunotherapy approaches to treat T1D would enhance personalized medical approaches to mitigate the effects of pathogenic T-cell–mediated diseases such as T1D. A promising approach is the application of chimeric antigen receptor (CAR) T cells, given its known mechanism and current use to treat other diseases such as hematological cancers.

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The Beginners Guide to COVID-19 mRNA Vaccines

Aug 24, 2021 10:30:00 AM / by Nancy Andon, MSc posted in PBMCs, Serum, T Cells, Plasma

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Part 2: How COVID-19 mRNA Vaccines Trigger Immunity

In Part 1 of our blog series, we described what an mRNA vaccine is, and how it works.

In Part 2, we will explain how receiving the mRNA COVID-19 vaccine triggers the human immune system to start producing antibodies and facilitates long-term protection.

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The Beginners Guide to COVID-19 mRNA Vaccines

Aug 17, 2021 10:30:00 AM / by Nancy Andon, MSc posted in Cryopreservation, PBMCs, Serum, Plasma

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Part 1: What is an mRNA Vaccine?

Vaccination is one of the most successful public health initiatives in history. Vaccine-preventable diseases are at or near an all-time low. So why are some people so hesitant to receive the COVID-19 vaccine?

It turns out that vaccine hesitancy is as old as vaccination itself. The unknown can be scary, and while modern humans may live in the “Age of Information”, most of us realize that not all information is reliable. Fortunately, help is on the way! In this 2-part blog series, the experts at HemaCare break down precisely what a mRNA vaccine is and how it works to protect those who get it.

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COVID-19 Vaccine Series Launch Heralds New Era of Research

Aug 10, 2021 10:15:00 AM / by Nancy Andon, MSc posted in Cryopreservation, PBMCs, Serum, Plasma

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The COVID-19 pandemic upended daily lives around the world. Now that we have working vaccines, a new phase has begun in the battle against the deadly virus. Scientists are striving to gather in-depth information about vaccine immune response.

Data collected at the University of Oxford [1] shows that approximately 30.0% of the world population has received at least one COVID-19 vaccine, while just over 15.5% are fully vaccinated. Less developed countries lag far behind more developed nations in their vaccination rates. Only 1.1% of people in low-income countries have received at least one vaccine dose, while the most developed nations are now reaching vaccination rates of 60-70% of their population. [1] And even while countries race to vaccinate as many people against COVID-19 as possible, new strains of the virus are emerging, while vaccine hesitancy slows the global effort to eradicate the disease.

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New Study Suggests Hematopoietic Stem Cells Transplantation is Effective for Patients with SPSD

Jul 27, 2021 10:15:00 AM / by Stacy Matthews Branch, DVM, PhD posted in Autoimmune Disorders, Stem Cells

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Research from a new study has shown that an autologous non-myeloablative hematopoietic stem cell transplantation in patients with stiff person spectrum disorder might be safe and effective.

Stiff person syndrome or stiff person spastic disorder (SPSD) is a progressive autoimmune neurological disorder characterized by painful and debilitating episodic muscle spasms and stiffness.

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