Pluripotent stem cells offer a new prototype for Age Related Macular Degeneration modeling and therapies.
The Promise of Pluripotent Stem Cells for Age Related Macular Degeneration
Jun 30, 2014 1:00:47 PM / by Shweta posted in aging, cellular reprogramming, iPSCs, Stem Cells, tissue engineering, Basic Research
Regeneration of Aged Thymus: A Hope to Fight Aged Immune System
May 28, 2014 1:00:25 PM / by Maria posted in aging, Cell Therapy, Stem Cell Therapy, Stem Cells, T Cells, T lymphocytes, thymus, tissue engineering
Forced expression of a single transcription factor, FOXN1, can regenerate an aged thymus, leading to normal production and differentiation of T cells.
T Cell Immune Response Affected by Aging
May 12, 2014 1:00:18 PM / by Maria posted in aging, lymphocytes, Basic Research
T lymphocytes, as a component of the immune system, play a vital role in defending our body against intracellular pathogens, such as viruses, intracellular bacteria or parasites. In a previous blog we mentioned that cellular functions can abate with aging and cause the marked reduction in immune system responsiveness. These changes have been associated with increased morbidity and mortality in the elderly population from infectious diseases[1].