Blog | HemaCare

Stem Cells May Aid ALS Treatment

Jun 4, 2018 10:09:00 AM / by Stacy Matthews Branch, DVM, PhD posted in ALS, hematopoietic stem cells, Stem Cells


New research shows the potential regenerative power of hematopoietic stem cells in ALS and may be a feasible treatment approach in the future.

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a neurological disease characterized by the progressive destruction of motor neurons, leading to disability and later death. There is no cure for the disease, and the only FDA-approved treatment (riluzole) adds only an additional few months of life to patients with ALS. Many factors are associated with the development of ALS, yet the exact causes of ALS development remain poorly understood.

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Bone Marrow-derived Mesenchymal Stem Cells May Put the Brakes on ALS

May 2, 2016 1:00:07 PM / by Steffen Porwollik posted in ALS, amyotrophic lateral sclerosis, autologous stem cell therapy, Bone Marrow, bone marrow, bone marrow-derived stem cells, clinical trial, Lou Gehrig's disease, neurotrophic factor, Stem Cell Therapy


A new report shows that autologous therapy with bone marrow-derived mesenchymal stem cells secreting neurotrophic factors may slow progression of amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig’s Disease).

Henry Louis (“Lou”) Gehrig had a stellar career as first baseman for the New York Yankees. In 17 seasons, through the 1920’s and 1930’s, he hit almost 500 home runs. He seemed indefatigable and powerful, nicknamed “The Iron Horse”. That is, until, in the second half of the 1938 season, his abilities sharply deteriorated. In June 1939, he was diagnosed with amyotrophic lateral sclerosis (ALS). Lou Gehrig died two years later.

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