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Stem Cell Models for Alzheimer’s Disease Enable Drug Discovery and Development

Feb 3, 2016 1:00:37 PM / by Karina Palomares posted in Alzheimer's disease, iPSCs, Stem Cells


Scientists evaluate new treatments of Alzheimer’s disease on neurons derived from iPSCs from patients.

Alzheimer’s disease is the leading cause of dementia, and has affected approximately 48 million people worldwide. Despite decades of research, we have yet to come up with a successful treatment. One major challenge in drug development for neurological diseases is access to a clinically relevant disease model. As stated in a recent WSJ article, results from animal testing often do not predict well what will happen in humans [1].  As a result, many promising drug candidates have been removed from further development because of safety concerns or lack of efficacy.

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Cord Blood a Possible Answer to Alzheimer's Disease

Jul 29, 2015 1:00:33 PM / by Maria posted in hippocampus, Alzheimer's disease, growth factors, research


Alzheimer's research is equal measure hope and frustration. Cord blood might be a much-needed solution. 

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Can Blood Plasma from the Young Reverse Ailments of the Old?

Jul 20, 2015 1:00:11 PM / by Maria posted in aging, Alzheimer's disease, clinical trials, GDF11, research


Experiments show that blood plasma from the young reverse age-associated cognitive declines. What ingredient make it possible?

It sounds like something out of a science fiction movie, or the mind of a researcher gone off the rails. But a series of intriguing discoveries hint that young blood may help treat problems associated with the elderly.

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