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Inducing Fas Ligand in Dendritic Cells Gives Them an Edge Against Inflammatory Bowl Disease

Jul 11, 2016 1:00:32 PM / by Dalia Gaddis posted in bacteria, crohn's disease, Inflammatory bowel disease, Innovation, research, T Cells, therapy

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Researchers find that dendritic cells transduced with Fas Ligand are effective in treating colon inflammation.

Dendritic cells are constantly sampling the lumen of the intestines for harmful bacterial. Once they find a threat, they migrate to the neighboring lymph nodes to activate T cells. Since our intestines contain hundreds of millions of bacterial cells, dendritic cells have developed to ignore the commensal bacteria that would not harm us. This “ignorance” or tolerance has proved essential for intestinal health. Breakdown of this tolerance results in inflammatory bowel diseases or IBD. We have previously written about how defective dendritic cells are to blame for the initiation of IBD.

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Cholesterol-lowering Drugs Protect the Heart and Prevent Against Gastric Cancer

Feb 8, 2016 1:00:59 PM / by Dalia Gaddis posted in bacteria, Cancer Immunology, Helicobacter pylori, research, Statins, stomach, Tumors

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Researchers find that statins can reduce gastric cancer by affecting the main causative bacteria, Helicobacter pylori.

It's a scientist’s dream: to find that an already known medication can treat a second and completely unrelated disease. This is what a research group recently may have found. The cholesterol-lowering drugs, statins, might reduce gastric cancer incidence by affecting the bacteria that causes the cancer.

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