Colorectal cancer (CRC) is the fourth most common type of cancer in the U.S. , but screening and early diagnosis have helped to reduce the death rate from CRC in the U.S. However, developing and transitional countries experience increases in the incidence of CRC. The primary treatment approaches used (surgery, chemotherapy, radiotherapy) are associated with adverse events and poor survival rates.
Preterm labor is a major cause of and infant mortality and long-term medical complications in offspring. Premature activation of the maternal immune system may stimulate cervical dilatation and activation of the uterine smooth muscle, leading to preterm delivery. Normal labor involves an increase in the expression of uterine-derived pro-inﬂammatory cytokines and chemokines that activate maternal peripheral leukocytes. Leukocytes then increase within the uterus and stimulate the cervical and uterine conditions that lead to delivery of the baby. Better characterization of these biochemical and cellular events may provide information that can be used to screen or predict the risk of preterm labor.
There is an ever increasing desire to understand the medicinal properties of marijuana. The components of marijuana are numerous; however, the more widely known class of compounds with medicinal activity are cannabinoids. Scientists continue to search for the mechanisms of these cannabinoids in various diseases including cancer and inflammatory conditions.
Cardiovascular diseases are a leading cause of death worldwide. There are various risk factors for cardiovascular disease such as obesity, physical inactivity, smoking, and diabetes. The risk of cardiovascular disease and stroke in patients with type 2 diabetes is more than twice that of people without diabetes.