Blog | HemaCare

HemaCare Aids Strategy for Boosting Gene Therapy Efficiency

May 21, 2019 10:06:00 AM / by Nancy Andon, MSc posted in Gene Therapy, bone marrow stem cells, CD34, Stem Cells, mobilized peripheral blood

0 Comments

An independent publication cites the use of bone marrow and mobilized peripheral blood sourced from HemaCare in a study aimed at improving the efficiency of resource consumption in gene therapy.

The publication, published in the journal Molecular Therapy, focuses on the use of lentiviral vector (LV) to introduce corrected versions of defective genes into stem cells. The goal of gene therapy is to transplant these stem cells into people suffering from genetic disease, in hopes of restoring the function of the faulty gene. One of the main challenges in this clinical strategy is the cost; substantial amounts of LV are needed to modify a therapeutically effective dose of stem cells.

Read More

Intracerebral Hemorrhage: How Mononuclear Cells May Play a Role in Treatment

Oct 17, 2016 1:30:23 AM / by Stacy Matthews Branch, DVM, PhD posted in Bone Marrow, bone marrow mononuclear cells, bone marrow stem cells, intracerebral hemorrhage, Mononuclear Cells, research

0 Comments

One of the most life-threatening forms of stroke is intracerebral hemorrhage (ICH). This type of stroke is caused by bleeding that occurs within the brain tissue. Common causes of brain hemorrhage include brain tumors, brain trauma, and aneurysms. Effective treatment for patients suffering from intracerebral hemorrhage is lacking. The usefulness of various cell types to treat the effects of ICH continues to be studied. Bone marrow mononuclear cells are considered prime candidates for cell therapy for patients with ICH because they can be quickly collected and processed from bone marrow.

Read More

New Research Shows Hope for Cancer Patients

Oct 12, 2016 1:00:52 AM / by Stacy Matthews Branch, DVM, PhD posted in Bone Marrow, bone marrow stem cells, human cord blood stem cells

0 Comments

 

F or cancers such as leukemia (cancer of the white blood cells), chemotherapy followed by stem-cell transplantation to repopulate with healthy cells is the treatment of choice. There are various sources of stem cells including bone marrow , circulating blood, and umbilical cord blood. Researchers reviewed hundreds of cases of leukemia as well as other blood disorders. They found that those patients who received stem cells from human cord blood , had survival rates that were similar to or higher than those who received other types of stem cell transplants.
Read More

CD34+ or CD34−: Does it Really Matter?

Sep 26, 2016 1:13:22 AM / by Stacy Matthews Branch, DVM, PhD posted in Bone Marrow, bone marrow stem cells, CD34, progenitor cells, Stem Cells

0 Comments

CD34 is a glycoprotein located in cell membranes, and was initially found to be present in hematopoietic stem and progenitor cells. CD34 is a commonly used marker for stem cells; however, there have been some experiments in the past that questioned whether CD34 is in fact a marker for these cells because some progenitor cells do not have CD34 (CD34‒), yet can produce CD34+ stem cells. Studies over the years show that CD34+ cells provide the hematopoietic activity (blood cell formation) in bone marrow and the development of specialized blood cells types (differentiation). Transplantation of patients with bone marrow that has a higher concentration of CD34+ cells is associated with faster engraftment (growth of healthy blood stem cells) and less related complications.

Read More

Responsibly Advancing Stem Cell Research

Aug 24, 2016 4:49:27 PM / by Stacy Matthews Branch, DVM, PhD posted in bone marrow stem cells, induced pluripotent stem cells, research, stem cell research, Stem Cell Therapy

0 Comments

The concept of stem cell therapies has existed for decades including the transplantation of bone marrow stem cells for patients with multiple myeloma and leukemia. However, controversy has arisen and persists in regards to the use of stem cells from human embryos. Due to the debates and ethical concerns with the use of human embryonic stem cells, new research is uncovering possible alternatives, such as induced pluripotent stem cells (stimulation of a patient’s own cells to behave as embryonic stem cells).

Read More

Subscribe Here!

Posts by Topic

see all

Recent Posts