Blog | HemaCare

HemaCare Donor Recruitment Helps Solve Lung Cancer Puzzle

Jun 30, 2020 10:04:00 AM / by Nancy Andon, MSc posted in Cancer

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A recent independent study cited using whole blood collected from HemCare donors to carry out research into how lung cancer suppresses the immune system. [1]

Scientists at a Boston-based pharmaceutical company have been trying to puzzle out exactly how lung cancer cells are able to suppress the immune system, and prevent it from launching an effective response. While previous research has exposed cancer-associated fibroblasts (CAFs) as the primary culprits in this process, there is still little real knowledge of how these cells are able to interfere with immune cell function.

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Possible New Improvements for Acute Myeloid Leukemia Treatment

May 26, 2020 10:02:00 AM / by Stacy Matthews Branch, DVM, PhD posted in Cancer, Blood Disorders

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Researchers continue to build on success of treating AML patients with an alkaloid (HHT) derived from a conifer tree.

Acute myeloid leukemia (AML) is not one disease but a group of hematopoietic neoplasms with varying genotypes, yet similar phenotypes. The cancer arises from hematopoietic stem cells that normally differentiate into myeloid cells such as granulocytes, monocytes, and erythrocytes.

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HemaCare PBMCs Aid HPV Cancer Research

Apr 7, 2020 10:07:00 AM / by Nancy Andon, MSc posted in Cancer, PBMCs, T Cells

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Cell therapy starting materials sourced from HemaCare are being used to support studies focused on the selective expansion of tumor-specific T cells.

In a recent article, [1] researchers at a Cambridge, MA biotech company describe their work with a fusion protein designed to specifically activate and expand killer T cells that recognize human papilloma virus associated (HPV+) head and neck cancer cells.

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HemaCare PBMCs Power Exosome-based Cancer Immunotherapy

Mar 3, 2020 10:02:00 AM / by Nancy Andon, MSc posted in Cancer, PBMCs, Immunotherapy (Immunology)

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In a recent study, scientists at UCLA medical school cited using HemaCare sourced PBMCs for their research into a novel cancer immunotherapy strategy. [1]

This promising new strategy is based on cellular structures known as exosomes, which are small membrane-bound packets used to deliver protein “messages” from cell to cell. Because exosomes are known to facilitate cell-to-cell communications, researchers were keen to figure out whether they could be used to communicate the information immune cells need to target cancer.

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New T Cell Therapy Raises Hopes for Universal Cancer Treatment

Feb 25, 2020 10:12:00 AM / by Nancy Andon, MSc posted in Cancer, Cell Therapy, T Cells

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A new type of T cell capable of recognizing and killing most human cancer cells has just been discovered. Researchers at Cardiff University in Wales hit upon the entirely new class of T cell while examining immune cells at a local blood bank. [1] This T cell carries a novel T cell receptor (TCR) which recognizes most cancers, while ignoring healthy cells.

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