Blog | HemaCare

New Study Shows Cancer Cells Reverting to Stem Cells

Nov 2, 2021 10:30:00 AM / by Stacy Matthews Branch, DVM, PhD posted in Cancer, Stem Cells

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Scientists in Japan created a new tool to study how cancer cells will hide in the body, making it easier to create new cancer cells after treatment.

According to the Centers for Disease Control, cancer is one of the top 5 causes of death in developed countries. Although many advances have been achieved regarding treatment options for different types of cancer, preventing recurrence and bolstering long-term survival in patients with advanced forms of cancer remains a challenge. The persistence of cancer stem cells in the body, which are resistant to conventional treatments, appears to be an important factor leading to cancer recurrence.

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HemaCare T Cells Support Study on Cell Therapy Consistency

Oct 5, 2021 10:30:00 AM / by Nancy Andon, MSc posted in Leukopak, Cancer, T Cells

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A new publication by scientists at the Cell and Gene Therapy Catapult in the UK cites the use of HemaCare-sourced CD3+ T cells for their cancer immunotherapy research.

The successful commercialization of gene-modified cell therapies relies in part on being able to manufacture a consistent product. Many cell and gene therapy developers use lentiviral vector delivery systems to impart the therapeutic gene modifications necessary to making their therapies effective.

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Brain Cancer Vaccine Passes Phase I Human Trial

Sep 21, 2021 11:00:00 AM / by Stacy Matthews Branch, DVM, PhD posted in Cancer, T Cells

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The vaccine was designed to assist a patient’s immune system target brain tumors more effectively and efficiently.

Gliomas are brain cancers that are considered rare disorders that affect 6.6 out of 100,000 individuals yearly worldwide.

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Cancer CAR T Cell Therapy Adapted to Help Fight Threatening Fungal Infections

Sep 14, 2021 10:00:00 AM / by Stacy Matthews Branch, DVM, PhD posted in Cancer, CAR-T, T Cells, Immunotherapy (Immunology)

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Cryptococcus fungi infections can be fatal as the immune system struggles to fight off the invaders, but through immunotherapy called CAR T cell therapy, researchers are seeing positive results.

Cryptococcosis, a systemic fungal infection, is caused by the polysaccharide encapsulated yeasts Cryptococcus gatti and Cryptococcus neoformans. The disease can cause pneumonia and meningitis, as well as pathology in other tissues.

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"Invisible" Stem Cells May Help Enhance Immunotherapies to Destroy Tumors

Jul 20, 2021 10:15:00 AM / by Stacy Matthews Branch, DVM, PhD posted in Cancer, Stem Cells

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Scientists at UC San Francisco discovered a new method for controlling the natural killer cells in the immune system through tissue implants and cell therapies that can enhance immunotherapies’ ability to detect/destroy cancerous tumors.

A major challenge with regenerative medicine is the immune system’s ability to reject implanted tissues recognized as non-self. Immunological rejection is a significant obstacle that stunts success in stem cell transplantation. Overcoming immune rejection of transplanted stem cells can support the development of off-the-shelf immunotherapies that can be used in any patient.

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