Blog | HemaCare

HemaCare Rings in the New Year with New Headquarters and a Cutting-Edge Collection Center

Feb 5, 2019 10:08:00 AM / by Nancy Andon, MSc posted in GMP, Apheresis, Cell Therapy, cGMP, clinical grade compliance, clinical trial

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HemaCare Corporation’s new global headquarters is officially open for business! The company started 2019 in a brand new 40,000 square foot space in a newly modernized 44-acre corporate campus located in the heart of the San Fernando Valley at Northridge. The design and construction of the cutting-edge facility provide a spacious workspace that promotes the well-being of its occupants, while significantly expanding the company’s on-site capabilities.

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Getting personal with your cancer therapy

Aug 3, 2016 3:35:05 AM / by Stacy Matthews Branch, DVM, PhD posted in Cancer, Cancer Immunology, cancer immunotherapy, Cell Therapy, clinical trial, Innovation

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For many years, cancer therapy has been tackled with a more or less universal approach. The drawback of this approach to therapy is the wide range of different responses to a given therapy. The concept of personalized medicine, tailoring treatment to a patient’s specific characteristics, has been envisioned and desired for many years. It is now being studied and implemented to increase successful responses to therapy, including cancer therapy.

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Bone Marrow-derived Mesenchymal Stem Cells May Put the Brakes on ALS

May 2, 2016 1:00:07 PM / by Steffen Porwollik posted in amyotrophic lateral sclerosis, autologous stem cell therapy, Bone Marrow, bone marrow, bone marrow-derived stem cells, clinical trial, Lou Gehrig's disease, neurotrophic factor, Stem Cell Therapy

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A new report shows that autologous therapy with bone marrow-derived mesenchymal stem cells secreting neurotrophic factors may slow progression of amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig’s Disease).

Henry Louis (“Lou”) Gehrig had a stellar career as first baseman for the New York Yankees. In 17 seasons, through the 1920’s and 1930’s, he hit almost 500 home runs. He seemed indefatigable and powerful, nicknamed “The Iron Horse”. That is, until, in the second half of the 1938 season, his abilities sharply deteriorated. In June 1939, he was diagnosed with amyotrophic lateral sclerosis (ALS). Lou Gehrig died two years later.

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Lung Cancer Patients Live Longer with Drug Targeting T cells

Feb 24, 2016 1:00:46 PM / by Daisy posted in Cancer Immunology, clinical trial, PD-1, PD-L1, pembrolizumab

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Pembrolizumab, a newer drug, harnesses T cells to tackle cancer. For certain lung cancer patients, this means having twice the lifespan than that accorded by chemotherapy! 

For patients battling lung cancer, the majority are of the non-small-cell lung carcinoma (NSCLC) subtype. Among these, a subgroup of tumors produce a protein, PD-L1, which enables escape from attack by the patient’s immune system (see here). Specifically, PD-L1 binds to PD-1 receptors on T cells, thereby preventing T cells from activating, proliferating, and/or producing cytokines, so that T cells do not mount an attack towards the PD-L1-positive tumor cells.

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Developing Antibody Drugs Against B-cells

Jan 11, 2016 1:00:44 PM / by Daisy posted in Cancer Immunology, chronic lymphocytic leukemia, clinical trial, CLL, obinutuzumab, research, rituximab

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The success of rituximab as an antibody drug targeting B-cells has led to the development of obinutuzumab – a similar, third-generation drug

Chronic lymphocytic leukemia (CLL) is a B-cell disease that is currently incurable. Combining targeted drugs has improved overall survival. However, not all patients benefit, because B-cells can harness any of several mechanisms to gain unrestricted proliferative capacity (see here).

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