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Stem Cells and Gene Editing Technology Together Create a Mini-Kidney in the Lab

Nov 30, 2015 1:00:54 PM / by Shweta posted in disease modeling, disease-state cells, induced pluripotent stem cells, Innovation, Regenerative Medicine, Stem Cells

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Gene editing technology along with stem cells helped scientists develop a miniature scale kidney

In the past, researchers already developed complex kidney structures using stem cells. Now, the main aim of kidney tissue engineering is to develop new therapies to repair kidney damage and thus reduce the need for dialysis and transplantation. Recently, scientists at University of Washington in collaboration with Brigham and Women's Hospital and Harvard Stem Cell Institute (HSCI) have grown mini-kidneys in the laboratory [1]. The ex-vivo kidney could be used to study abnormalities in kidney development, chronic kidney disease, and the effects of toxic drugs on acute and chronic kidney conditions.

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