Blog | HemaCare

Cross-Dressing: Dendritic Cells taking on the Job of the Donor Cells

Aug 29, 2016 1:55:05 PM / by Stacy Matthews Branch, DVM, PhD posted in Dendritic Cells, donor cells, T Cells, Uncategorized


A major hurdle for recipients of donor tissues and organs is rejection of the transplant by the recipient’s immune system. It has been thought that dendritic cells from the donor tissues directly trigger the recipient’s T cell response against the transplant. However, it is now known that only a low number of donor dendritic cells actually reach the recipient’s immune system tissues. Recent studies unveiled how such a small number of dendritic cells could elicit rejection responses.

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