About 50% of stem cell transplant patients develop GVHD. A clinical trial using a modified stem cell graft reduced this hazard to 9%.
Improved Outcome for Stem Cell Transplantation in Leukemia
Sep 28, 2015 1:00:14 PM / by Daisy Goodrich posted in GVHD, Bone Marrow, clinical trial, leukemia, Stem Cells, T Cells, Basic Research
Donor T regs Friendly Towards Host Dendritic Cells
Apr 23, 2014 1:00:50 PM / by Daisy Goodrich posted in GVHD, Dendritic Cells, T Cells, Basic Research
Dendritic Cells: Rabble-Rousers after Stem Cell Transplantation
Apr 16, 2014 1:00:50 PM / by Daisy Goodrich posted in GVHD, proteasome inhibitors, T Cells, Basic Research
Stem cell transplantation is often the only option for patients who have certain blood cancers. Unfortunately, this last resort can sometimes bring more harm than good. Graft versus host disease (GVHD), is a common complication that affects 50% of transplant patients. GVHD is not an issue if the patient's own stem cells are transplanted back. However, GVHD can become an issue, sometimes fatal, when stem cells from another donor are used.