Sickle cell disease refers to a group of genetic blood disorders mainly affecting people of African, Mediterranean, Middle Eastern, and Caribbean decent. Those with sickle cell disease carry the abnormal hemoglobin S in their red blood cells due to a mutation of the β-globin gene. Instead of having flexible, disc-shaped red blood cells, affected individuals have characteristic sickle-shaped, more rigid cells that cause disturbances in blood flow and tissue oxygenation.
Patient with Sickle Cell Disease Responds Favorably to Gene Therapy
Apr 11, 2017 11:01:21 AM / by Stacy Matthews Branch, DVM, PhD posted in Hematopoietic History, biomedical research, Stem Cell Therapy, Stem Cells, Blood Disorders, Basic Research
Science Beneath the Successful Cord Blood Banking
Aug 27, 2014 12:11:33 PM / by Shweta posted in Hematopoietic History, Cord Blood, Stem Cells, white blood cells, Basic Research
Safe cord blood banking: A stock for baby’s long term health
Manipulation of Hematopoietic Stem Cells for Regenerative Medicine
Mar 5, 2014 4:00:08 AM / by Maria posted in Hematopoietic History, Cell Therapy, Cord Blood, iPSCs, Regenerative Medicine, Stem Cell Therapy, Stem Cells
The what, why and how hematopoietic stem cells are dominating the regenerative medicine space
Hematopoietic History: The First Stem Cell Transplant
Jan 2, 2014 8:00:32 AM / by Maria posted in Hematopoietic History, Peripheral blood cells, Stem Cells
Post WWII many soldiers owed their lives to spleen and bone marrow stem cell transplants. Much later we find out that it was the presence of hematopoietic stem cells that was responsible for cell re-population.