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Virion-Associated Vpr Restores the Ability of HIV-1 to Infect Dendritic Cells

May 9, 2017 10:20:59 AM / by Stacy Matthews Branch, DVM, PhD posted in bioresearch, Dendritic Cells, HIV-relevant cell populations


The HIV-1 virus produces various proteins needed for infection and replication in human cells. Some of these are accessory proteins that mainly help the HIV-1 virus to evade the immune system defenses and to overcome factors that function to restrict or inhibit infection. One protein that may function in this way is the Vpr protein, which is a virion (infective virus form)-associated protein.

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