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Tetraspanin CD37: a New Player in the Immunotherapeutic Arsenal Against B Cell Lymphoma

Mar 14, 2016 1:00:46 PM / by Dalia Gaddis posted in Cancer, immune system, tetraspanin, Tumors, Basic Research, Immunotherapy (Immunology)

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Researchers discover a missing link in the progression of B cell lymphoma.

Diffuse large B cell lymphoma is the most common form of non-Hodgkin lymphoma (NHL), contributing to about 30% of the cases in the United States. It is an aggressive form of NHL that usually presents itself with severe swelling of the lymph nodes at the sites being affected. The most common therapy for the disease is a combined immunotherapy with rituximab and radiotherapy. Secondary therapies are also used for patients who do not respond to the initial therapy, or who relapse after a period of remission.1

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Gene Editing in Stem Cells Corrects a Troubling Disorder

Aug 13, 2014 1:00:41 PM / by James Sanchez posted in immune system, Stem Cells, T Cells, zinc finger nucleases, Basic Research

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By targeting a defective gene in stem cells, researchers opened a new possibility in correcting genetic disorders.

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Dendritic Cells in Treatment for Type 1 Diabetes

Jun 11, 2014 1:00:47 PM / by Maria posted in immune system, type 1 diabetes, Basic Research

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New research demonstrates that delivery of engineered therapeutic dendritic cells that target lymphoid sites of tolerance induction can compensate for failing tolerance in the patient.

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