Blog | HemaCare

HemaCare PBMCs Aid Development of Novel Cancer Immunotherapy

Aug 4, 2020 10:01:00 AM / by Nancy Andon, MSc posted in Cancer, PBMCs, Immunotherapy (Immunology)


A paper published in the journal Blood cites the use of HemaCare-sourced peripheral blood mononuclear cells (PBMCs) to test a murine model of a new antibody-based cancer immunotherapy.

Multiple myeloma (MM) is a life-threatening disease that accounts for 10-15% of all blood-based cancers. The disease occurs when a specific group of white blood cells, known as plasma cells, become malignant. T cell therapy has shown some promise in treating the disease on a temporary basis, but with very few cancer-specific targets identified, MM remains incurable.

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Customized Immunotherapy Shows Promise for Lung Cancer

Jul 28, 2020 10:04:00 AM / by Stacy Matthews Branch, DVM, PhD posted in Cancer, T Cells, Immunotherapy (Immunology)


A recent Phase I trial studying the effect of TIL therapy on lung cancer shows promising results for long-term patient remission.

Tumor-infiltrating lymphocytes (TILs) are T-cells that infiltrate solid tumors to attack tumor antigens. Still, the tumor microenvironment inhibits T-cell growth leading to low numbers of the cells and insufficient immune response. Checkpoint proteins on tumor surfaces, such as PD-1, can also further inhibit T-cell response in tumors. However, in the case of melanoma, scientists have been able to achieve a complete remission with TILs that can last over a decade.

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Discussing Therapeutic Options for Novel Coronavirus (COVID-19)

Mar 24, 2020 10:04:00 AM / by Stacy Matthews Branch, DVM, PhD posted in T Cells, Vaccine Research, Immunotherapy (Immunology)


While the world waits for a coronavirus vaccine, scientists are looking to viral and cell therapy treatments for a solution.

Since China began reporting COVID-19 cases to the World Health Organization (WHO), the novel virus has since spread globally. With the declaration of COVID-19 as a global pandemic, announcements about efforts to develop a coronavirus vaccine are ongoing and constant.

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Memory T Cells in Mice Aid Immunity During Periods of Food Scarcity

Mar 17, 2020 10:12:00 AM / by Stacy Matthews Branch, DVM, PhD posted in T Cells, Immunotherapy (Immunology)


Researchers are studying the importance of white adipose tissue and its role in storing memory T cells.

The idea that if you don’t eat enough, you’ll get sick may be true in some ways, but there is new information available revealing that the immune system may have a strategy to keep fighting infectious agents even when food is scarce.

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HemaCare Bone Marrow Mononuclear Cells Help Unravel Immunological Mystery

Mar 10, 2020 10:05:00 AM / by Nancy Andon, MSc posted in Bone Marrow, Immunotherapy (Immunology)


Scientists in New York studying allergic disease have just published work citing the use of HemaCare-sourced bone marrow mononuclear cells for their research into the mechanisms of immunological memory.

The immune system is a wonderfully complex assembly of interacting cells and tissues that protect us from disease. To function properly, the cells within this system must detect and remember a wide variety of triggering agents.

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