Blog | HemaCare

A report out of Nature Communications suggests a correlation between the use of low TMB and an increased survival rate among glioblastoma patients may be due to changes in the immunological status of tumor post therapy.

Tumor mutation burden (TMB) is the frequency of certain protein (tumor antigen)-altering mutations within tumor genes. The production of more tumor antigens increases the chances that one or more of those can be recognized and reacted upon by the immune system. Highly mutated tumors produce many antigens that can stimulate T cells to respond to the antigens.

A study showed that patients who have received immunotherapy for non-small cell lung cancer can get more than one immune relative side effect.

The most common form of lung cancer is non-small cell lung cancer (NSCLC). It is divided into four stages, depending on the lung tumor’s size and location(s). Surgery and chemotherapy are common approaches to treatment, but newer approaches such as targeted therapy and immunotherapy provide promising survival benefits for patients with NSCLC.

HemaCare scientists have just published a white paper on a new raw material sourcing paradigm that they hope will transform the industry.

The publication centers on dedicated donors; recallable donors who are reserved to specific research programs. The basic premise is that clients will be able to reserve self-identified recallable donors who possess physiological or demographic traits deemed beneficial to a particular research program.

Isolated immune cell populations support a wide variety of research and cell therapy applications. Because purification and preliminary characterization of immune cell subsets can be time-consuming and costly, many researchers prefer to purchase isolated immune cells rather than raw materials.

You wanted cell isolation – we delivered!

In 2021, the word isolation tends to have garnered a negative connotation. However, when a cell biologist thinks of isolation, specifically cell isolation, they think of it as a wonderful thing.

After all, isolated cells are a sought-after starting material that allows scientists to dive deeper into their research and accelerate their studies. At HemaCare, we heard your requests and can now deliver isolated immune cells from full leukopak collections to your doorstep!