Blog | HemaCare

Stem Cell-Like Function of Adult Immune Cells Stimulate Healing

Apr 9, 2018 10:05:00 AM / by Stacy Matthews Branch, DVM, PhD posted in Macrophages, Stem Cells, immune cells

0 Comments

New research suggests that wound fluid induced macrophage clustering shows improved healing.

Tissue damage is repaired by the proliferation of normal cells, tissue stem cell maturation, and scar formation. However, the inflammation associated with tissue damage or injury promotes cell plasticity as part of the tissue repair process. Fibroblasts that are critical for wound healing are mesenchymal cells that are actually derived from myeloid cells such as macrophages. Macrophages are immune cells that are the first line of defense against pathogens. They are also important in wound healing and inflammatory processes.

Read More

Cancer Treatment That Boosts Macrophage Cancer-Fighting Action

Mar 22, 2017 3:21:32 PM / by Stacy Matthews Branch, DVM, PhD posted in Cancer, Cytotoxic T Cells, Macrophages

0 Comments

Many therapeutic strategies are continuously being investigated to find the means to effectively treat cancer. Immunotherapeutic approaches are emerging as very valuable options for patients with different types of cancer. Many of the approaches involve targeting the adaptive immune system. The adaptive immune system involves targeting specifically identified cells by cytotoxic T cells and represents a specialized attack on invading and pathogenic (disease-causing) cells and molecules.

Read More

Palmitate-Induced Suppression of IGF binding protein-3 Leads to Liver Inflammation

Feb 6, 2017 8:16:08 AM / by Stacy Matthews Branch, DVM, PhD posted in Inflammation, Macrophages, Monocytes, stem cell research, Basic Research

0 Comments

Insulin-like growth factors (IGFs) are hormones resembling insulin and are important for normal cell growth and division. IGF-binding proteins (IGFBPs) regulate IGF action leading to changes in their effects in the body. IGF-binding protein-3 (IGFBP-3) is the most abundant of the IGFBPs and is made primarily in kupffer cells (specialized liver macrophages).

Read More

Distinct Gene Expression Profiles Shed Light on Leishmania-Macrophages Interactions

Nov 16, 2016 12:00:34 AM / by Stacy Matthews Branch, DVM, PhD posted in Macrophages, PBMCs, Peripheral blood cells, Stem Cells

0 Comments

Macrophages are formed from peripheral blood precursors called monocytes. They are the first line of defense against invading disease-causing organisms. Macrophages attack invaders by a process of phagocytosis (engulfment and breakdown of particles). They can also help initiate immune responses by T lymphocytes.

Read More

Myeloid Macrophages Implicated in Stress-Induced Memory Loss

Jun 22, 2016 1:00:28 PM / by Steffen Porwollik posted in Bone Marrow, Inflammation, Macrophages

0 Comments

A new study finds that chronic stress leads to recruitment of myeloid macrophages to the hippocampus, weakening the brain’s capacity for spatial memory. This finding may have broad implications for sufferers of stress-induced disorders.

Stress is part of our lives. Whether it occurs over finishing a term paper five milliseconds before the deadline, navigating the complicated social undercurrents in the office, juggling your teenaged offspring’s wishes against the budgetary restrictions of your existence, or getting delayed on the freeway on your way to an interview / concert / meeting / [insert absolutely crucial event here] – we all experience stress to varying degrees. Our bodies are equipped to handle stress, by pumping more oxygen to the brain, making us more alert and responsive.

Read More

Subscribe Here!

Posts by Topic

see all

Recent Posts