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Entry of Immune Cells via Tumor Endothelium May Enhance Melanoma Immunotherapy

Apr 12, 2017 9:56:16 AM / by Stacy Matthews Branch, DVM, PhD posted in Cytotoxic T Cells, melanoma immunotherapy, research


Melanoma is a skin cancer that arises from melanin-producing skin cells called melanocytes. While it is a common form of skin cancer, it is the deadliest. Given the immunogenicity of this skin cancer, its response to immunotherapy is highly studied. The level of immune cells in the peripheral blood may be a useful indicator of disease progression. However, the cells must actually infiltrate the tumors to have beneficial antitumor effects.

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