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Research Advances in Stem Cell Therapy for Rheumatic Diseases

May 21, 2018 10:02:00 AM / by Stacy Matthews Branch, DVM, PhD posted in stem cells, mesenchymal stem cells, mesenchymal

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There is promising research that shows adult stem cells may advance the treatment of rheumatic diseases such as rheumatoid arthritis and osteoarthritis. 

Stem cells are undifferentiated cells that can develop into any type of specialized cell, and are broadly divided into embryonic and adult stems cells. A current and well known application of stem cells includes the use of hematopoietic stem cells for bone marrow cancers. Stems cells are studied for their utility in treating a variety of diseases, particularly to treat organ damage and conditions involving a dysfunctional immune system. 

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Nanothin and Highly Porous Membranes Generate Cardiac Sheets from Stem Cells

Dec 28, 2015 1:00:31 PM / by Karina Palomares posted in cardiac, coculture, mesenchymal stem cells, research, stem cells

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Use of nanothin and highly porous membranes enables the efficient generation of homogenous, ECM-preserved, highly viable, and transfer-printable cardiac sheets from stem cells.

Pluripotent stem cells are renowned for their ability to divide indefinitely and their capacity to differentiate into many of the tissues of the body, raising the possibility that they may provide an unlimited source of cells for tissue replacement. However, development of a functional tissue is not a simple matter, since standard culture systems do not recapitulate a cell’s natural environment. Culture environments that encompass the molecular, structural, and physical factors regulating differentiation are necessary to achieve the full potential of stem cells.

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Curing Babies before Birth with Stem Cell Transplantation

Dec 16, 2015 1:00:14 PM / by Daisy posted in brittle bone disease, in-utero stem cell transplantation, mesenchymal stem cells, MSC, osteogenesis imperfecta, prenatal, research, Stem Cell Therapy

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A clinical trial will for the first time evaluate stem cell transplantation in unborn babies as curative therapy for osteogenesis imperfecta

It is estimated that 30,000 individuals in the US live with osteogenesis imperfecta (OI). Tagged as “brittle bone disease”, OI is caused by deficiencies in the skeleton building block, collagen. There is no cure; treatment consists of procedures to increase bone strength and mobility.

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Building Lungs in the Lab with Stem Cells

Aug 17, 2015 1:00:03 PM / by Shweta posted in Chronic obstructive pulmonary disease, mesenchymal stem cells, regenerative medicine, research, Stem Cell Therapy, stem cells, tissue engineering

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Stem cells discovery paves the way for the treatment of pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a major cause of significant morbidity and mortality worldwide. According to the World Health Organization (WHO), more than 64 million people around the world have moderate to severe COPD. It is now the third leading cause of death in the United States, responsible for around 5% of global deaths every year. It has been estimated that in the next 10 years the total death rate may rise by more than 30%.

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Transplanted hMSCs Improve Bladder Function

Nov 3, 2014 12:00:19 PM / by Shweta posted in bladder, Bone marrow, bone marrow, fibrosis, Independent validation, Innovation, mesenchymal stem cells, research, spinal cord injury, stem cell transplantation, stem cells

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A direct injection of hMSCs into the bladder wall prevents bladder fibrosis

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