Blog | HemaCare

Encapsulated human stem cell–derived beta cells: Promising treatment for Type I diabetes?

Sep 12, 2016 9:11:02 AM / by Stacy Matthews Branch, DVM, PhD posted in Cytotoxic T Cells, Dendritic Cells, Stem Cells, Blood Disorders, Metabolic Disorders

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The challenge to effectively and safely restore proper control of blood glucose (sugar) levels (referred to as glycemic control) in people with diabetes is ongoing. The standard treatment for type 1 diabetes remains to be proper monitoring of blood glucose levels with daily insulin injections. However, patient compliance often limits its effectiveness. Pancreas transplantation is associated with limited donor tissue availability and with side effects due to the immune system suppression needed to reduce the risk of tissue rejection.

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A New Hope Against Type I Diabetes: The T cells that Attack the Beta Cells in the Pancreas Have Been Found

May 16, 2016 1:00:15 PM / by Dalia Gaddis posted in Autoimmune Disorders, T Cells, Blood Disorders, Metabolic Disorders

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A long-awaited discovery leads researchers to find the pathogenic T cells that recognize and destroy pancreatic beta cells.

When it comes to autoimmune diseases, the patient’s main problem lies within. In such diseases, the immune system’s T cells go rogue and start attacking different organs, resulting in disease. Scientists are constantly trying to discover the identity of the autoimmune T cells as this may be the first step in a preventative therapy.

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Anti-Diabetes Drug “Suffocates” Pancreatic Cancer Cells

Nov 18, 2015 1:00:07 PM / by Karina Palomares posted in Cancer, Stem Cells, Blood Disorders, Metabolic Disorders

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New research suggests that metformin treatment could effectively eliminate pancreatic cancer stem cells that rely on oxygen-based metabolism for energy production.

Pancreatic cancer is the fourth most common cause of cancer death, because of its tendency to cause symptoms only at a late and advanced stage. There were 49,000 new cases of the disease in 2015 in the United States; only 7.2% survive beyond 5 years. In most cases, by the time signs and symptoms appear, complete surgical removal is not possible and the cancer has already spread to other organs. Thus, development of strategies for earlier detection and new treatments are necessary to improve the prognosis of pancreatic cancer patients.

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Pacifying NK Cells to Block Type 1 Diabetes

Jul 27, 2015 1:00:46 PM / by Daisy posted in Autoimmune Disorders, NK Cells, Humanized Mice, Blood Disorders, Metabolic Disorders

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Mice studies show that the use of an antibody towards NK cells could reduce the development of diabetes in susceptible populations.

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Clinical Trial Results for Type 1 Diabetes: Using Stem cells to Halt the Immune Attack

Feb 25, 2015 1:00:03 PM / by Daisy posted in Bone Marrow, Stem Cell Therapy, Stem Cells, Metabolic Disorders

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Redistributing immune cells through unpacking and repacking stem cells in the bone marrow shows promise in type 1 diabetes.

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