Blog | HemaCare

The Microbiome Knows a Colon Cancer's Secrets -- and It's Talking

Dec 9, 2015 1:00:52 PM / by Maria posted in microbiome, whole exome sequencing, zinc finger nucleases, Basic Research

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The mutational status of a colon cancer tumor affects the nearby bacteria, which can be analyzed non-invasively.

When you live in close quarters with roommates, you can't help but be affected by their actions. If they drink all the coffee, for example, you might go into some serious caffeine withdrawal.

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T Cells Receive an Education: Don't Attack Our Friendly Gut Bacteria!

Jul 6, 2015 1:00:31 PM / by Shweta posted in lymphocytes, microbiome, thymus, Basic Research

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New insights reveal how T cells know not to go after our beneficial microbiota

The immune system continuously protects the body from attack by foreign intruders. T lymphocytes play a crucial role in defending against any pathogen's assault. T cell development takes place in the thymus where these cells undergo "thymic education" and learn how to differentiate between self and foreign invaders. And yet the human gastrointestinal (GI) tract is inhabited with trillions of beneficial commensal bacteria. They help to regulate host nutrient metabolism and immune cell homeostasis, and they also protect from pathogen infection. Surprisingly, T cells learn to ignore beneficial microbiota in the intestine while they immediately try to recognize and eliminate any foreign invader in our body.

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Secrets of Crohn's Disease Revealed in the Human Microbiome

Oct 22, 2014 1:00:33 PM / by James Sanchez posted in disease-state products, genes, microbiome, Basic Research

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Intriguing research has zeroed in on the microbiome's role in a puzzling gastrointestinal disorder

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