Blog | HemaCare

Intracerebral Hemorrhage: How Mononuclear Cells May Play a Role in Treatment

Oct 17, 2016 1:30:23 AM / by Stacy Matthews Branch, DVM, PhD posted in Bone Marrow, Mononuclear Cells, Basic Research


One of the most life-threatening forms of stroke is intracerebral hemorrhage (ICH). This type of stroke is caused by bleeding that occurs within the brain tissue. Common causes of brain hemorrhage include brain tumors, brain trauma, and aneurysms. Effective treatment for patients suffering from intracerebral hemorrhage is lacking. The usefulness of various cell types to treat the effects of ICH continues to be studied. Bone marrow mononuclear cells are considered prime candidates for cell therapy for patients with ICH because they can be quickly collected and processed from bone marrow.

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Matchmaker for Stem Cells: Rejuvenation of Injured Heart by Antibody-Budded Nanoparticles

Nov 19, 2014 1:00:32 PM / by Shweta posted in Bone Marrow, Cell Therapy, Mononuclear Cells, Regenerative Medicine, Stem Cells, Basic Research


A "nanomatchmaker" for an alliance between the injured heart and traveler stem cells

Stem cell transplantations are emerging as a potential therapeutic option in the field of regenerative medicine. In one of our previous blogs, we have mentioned possible roles of stem cells in cardiac regeneration. In spite of several clinical trials, the success of stem cell transplantation in heart regeneration is still not nailed down completely. Some studies signified promising clinical outcomes, while others reported no difference. The role of bone marrow-derived mononuclear stem cells (BMMNCs) has also been investigated in patients with heart failure, and unfortunately results are not uniformly positive. Delivery of these therapeutic cells is always a major hurdle to achieve complete clinical success. Therefore, novel approaches are required for efficient targeted delivery of these cells to the site of injury.

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