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Matchmaker for Stem Cells: Rejuvenation of Injured Heart by Antibody-Budded Nanoparticles

Nov 19, 2014 1:00:32 PM / by Shweta posted in Bone marrow, bone marrow-derived mononuclear stem cells, cell therapy, Hematopoietic History, Independent validation, Innovation, myocardial infarction, Nanotechnology, regenerative medicine, research, stem cells

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A "nanomatchmaker" for an alliance between the injured heart and traveler stem cells

Stem cell transplantations are emerging as a potential therapeutic option in the field of regenerative medicine. In one of our previous blogs, we have mentioned possible roles of stem cells in cardiac regeneration. In spite of several clinical trials, the success of stem cell transplantation in heart regeneration is still not nailed down completely. Some studies signified promising clinical outcomes, while others reported no difference. The role of bone marrow-derived mononuclear stem cells (BMMNCs) has also been investigated in patients with heart failure, and unfortunately results are not uniformly positive. Delivery of these therapeutic cells is always a major hurdle to achieve complete clinical success. Therefore, novel approaches are required for efficient targeted delivery of these cells to the site of injury.

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