Conventional cancer treatment strategies are toxic to normal cells and lead to severe adverse effects for patients with cancer. To avoid exposure of chemotherapeutic agents to healthy tissue, controlled delivery of drugs targeting only tumor tissue would have significant clinical value. Research efforts in developing nanotechnology-based delivery systems can provide significant cancer treatment options; however, the choice of materials is crucial for their efficacy and safety.
Researchers have developed a streamlined technology for the enrichment and expansion of tumor-specific lymphocytes for adoptive immunotherapy.
A "nanomatchmaker" for an alliance between the injured heart and traveler stem cells
Stem cell transplantations are emerging as a potential therapeutic option in the field of regenerative medicine. In one of our previous blogs, we have mentioned possible roles of stem cells in cardiac regeneration. In spite of several clinical trials, the success of stem cell transplantation in heart regeneration is still not nailed down completely. Some studies signified promising clinical outcomes, while others reported no difference. The role of bone marrow-derived mononuclear stem cells (BMMNCs) has also been investigated in patients with heart failure, and unfortunately results are not uniformly positive. Delivery of these therapeutic cells is always a major hurdle to achieve complete clinical success. Therefore, novel approaches are required for efficient targeted delivery of these cells to the site of injury.