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Wasp Venom Peptide Targets Cancer Cell Membranes -- Selectively

Nov 2, 2015 1:00:04 PM / by Maria posted in drug discovery, natural products, research

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Research with an insect peptide challenges the popular belief that cancer cell membranes don't make good drug targets.

Cell membranes could use a little more respect. No one doubts that the inner machinery of cells is fascinating in its complexity, but membranes themselves are often viewed as rather boring containers that are pretty much the same no matter where you look. But membranes are actually highly complex structures consisting of hundreds of different lipids and proteins, often varying in composition among cell types. Still, even many cell biologists have perhaps not realized the implications this diversity could have for drug discovery.

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Toward a Functional Cure for HIV, with Help from Drug Discovery Under the Sea

Sep 23, 2015 1:00:32 PM / by Maria posted in HAART, natural products, research, Tat

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Thanks to a marine sponge, a novel way of combating HIV latency may have been found.

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Compound from Avocados May Target a Weak Spot in Acute Myeloid Leukemia

Jul 1, 2015 1:00:38 PM / by Maria posted in apoptosis, fatty acid oxidation, mitochondria, natural products, research

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Leukemia cells possess mitochondrial and metabolic alterations, which may be an Achilles' heel to a compound from avocados.

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"Magic" Mushrooms to Cast Away Prostate Cancer?

Jun 3, 2015 1:00:02 PM / by Maria posted in Cancer Immunology, clinical trials, interleukins, myeloid-derived suppressor cells, natural products, research

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For some patients in a clinical trial, mushroom powder may have reversed a troubling indication of prostate cancer reoccurrence.

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