Cincinnati Children’s hospital laboratory led a study that discovered a possible treatment for autoimmune diseases using T cells and CAR NK-cells.
Adaptive or acquired immunity is a specific response to pathogens. An important aspect of adaptive immunity and memory is the T-cell help to B cells. The support to B cells is provided by follicular helper CD4 T cells and entails helping B cells to produce antibodies against invading pathogens. Although follicular helper T cells are needed for long-term immunity, exaggerated responses of these T cells can lead to adverse reactions, including the promotion of autoimmune reactions.