Leukapheresis is a procedure to separate white bloods cells (including dendritic and progenitor cells) from a blood sample. Products obtained from leukapharesis procedures, leukopaks, are regularly used in the research setting. They are also used for cell therapy process development and clinically for certain treatment procedures for blood disorders. Another way to obtain white blood cells and platelets is to obtain them from the buffy coat.
Experiments show that blood plasma from the young reverse age-associated cognitive declines. What ingredient make it possible?
It sounds like something out of a science fiction movie, or the mind of a researcher gone off the rails. But a series of intriguing discoveries hint that young blood may help treat problems associated with the elderly.
Convalescent plasma therapy could be an effective treatment to fight against the Ebola virus
The Ebola virus causes a serious and deadly disease transmitted by animals and humans. The current Ebola epidemic is the largest outbreak in history, affecting many countries in West Africa. The Ebola virus likely originated in African fruit bats, but apart from zoonotic transmission it can also be transmitted from one human to another via direct contact such as through broken skin or mucous membranes, bodily secretions or fluids, or by contact with surfaces and materials (e.g. bedding, clothing) contaminated with these fluids. So far, no FDA-approved vaccine or medicine is available to treat Ebola infection. Only a few primary prevention measures are available which are largely based on symptomatic treatment and by avoiding direct contact with infected people and animals.
Acquiring DNA from plasma may avoid problems with safety and bias. In terms of sequencing, recent work has helped make this approach a reality.
Standard apheresis equipment is soon to be supplanted. What are the advantages in the next generation?