The saying goes when things get tough, take a deep breath. While this relaxation technique protects our health, apparently it also improves our immune system functions. Scientists discovered a new protein that increases the respiration of CD8 cytotoxic T cells, making them more fit to fight chronic infections and cancer.
Peripheral Blood Mononuclear Cells (PBMCs) can be used in drug screening. In Part I from this series, we discussed how they can be used to assay drug activity including effects on proliferation, viability, apoptosis, inflammation, and migration in healthy and disease cell models. There are related assays available to measure the effects of drug treatment and, especially for researchers that prefer to use human samples, peripheral blood mononuclear cells are often the cells of choice (PBMCs) are often the cells of choice. The advantages of using human cells initially are immense.