Blog | HemaCare

Misrecognition by Dendritic Cells Leads to Psoriasis

Jun 9, 2014 1:17:44 PM / by Daisy posted in Otezla, Psoriasis, research, skin, T Cells, TLR9


We discuss here the mechanism by which dendritic cells mistake human or self-DNA for pathogenic DNA. When self-DNA fragments form aggregates with LL37, it results in psoriasis.

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T Cells Contribute to 'Skin-Deep' Tolerance.

May 26, 2014 1:00:43 PM / by Daisy posted in CD3, research, skin, skin associated lymphoid tissue, tolerance


The skin is a specialized lymphoid organ, called “SALT” or “skin-associated-lymphoid-tissue”. There are 1 million T cells per square inch of skin and their dysfunction can result in disease.

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