Blog | HemaCare

IL-23-Polarized Dendritic Cells Drive Responses to Skin Immunization

Oct 19, 2016 5:08:18 PM / by Stacy Matthews Branch, DVM, PhD posted in Dendritic Cells, skin immunization

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Atopic dermatitis (AD) is an inflammatory skin disease that affects over 15% of children in the U.S. A common feature of AD is thickening of skin that is dry, irritated, and itchy. There is a disruption in the skin’s function as a barrier to injurious agents. Most cases of AD are allergy related. That is, the skin is sensitized to an offending substance (allergen). This skin immunization or allergic response is worsened by physical scratching action.

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