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Allergy Triggering IgE Gets a New Identity: Aggravating Inflammation in Lupus Patients

Mar 23, 2016 1:00:40 PM / by Dalia Gaddis posted in anti-DNA, auto-immune disease, IgE, research, self-reactive, SLE


Researchers find that self-reactive IgE can worsen autoimmune inflammation in systemic lupus erythematosus patients.

Systemic lupus erythematosus (SLE), or as commonly known as lupus, is a chronic autoimmune disease that affects multiple organs in the body. In this disease, the immune system generates self-reactive immune cells and antibodies against the body’s nucleic acids. Lupus symptoms vary dramatically from one patient to another but usually include fever, pain, fatigue, abutterfly shaped rash on the cheeks and nose and skin lesions. Lupus can cause serious damage to major organs such as the kidneys, lungs and heart. Currently, there is no cure, only treatments to keep symptoms under control. Treatment usually includes non-steroidal anti-inflammatory drugs, corticosteroids or immunosuppressive therapy.1

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PBMC Analysis Shows Cytomegalovirus is Contributory to Developing Lupus

May 20, 2015 1:00:42 PM / by Daisy posted in CMV, cytomegalovirus, lupus, research, SLE


Viral infections are important contributory factors leading to disease state in lupus. Through PBMC testing, scientists show that CMV is a culprit as well.

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